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Ethyl 2-Butynoate (CAS 4341-76-8): Applications in Organic Synthesis and Methanogenesis Inhibition


Ethyl 2-butynoate cas:4341-76-8, also known as ethyl tetrolate, is an electron-deficient alkyne ester with a molecular weight of 112.13 g/mol .

Key applications include:
Precursor in synthesizing tricyclic aziridines, alkenylsilanols, and cyclopentene dicarboxylates .
Methanogenesis inhibitor and key reagent in Rh(I)/H8-BINAP-catalyzed 1,3-diene preparations .
Intermediate in stereoretentive cross-coupling reactions and total syntheses of natural products like waixenicin A .

Ethyl 2-butynoate cas:4341-76-8, a 2-alkynoate is a methanogenesis inhibitor. It is an electron deficient internal alkyne that has been reported to undergo codimerization with alkenes to form 1,3-dienes catalyzed by rhodium(I)/H8-BINAP complex.

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Last Update : 15 May 2025 3:35 PM
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